Skip to main content
Log in

Properties of bovine interferons

  • Short Communications
  • Published:
Experientia Aims and scope Submit manuscript

Summary

This study was done in an attempt to elucidate some of the properties of bovine IFNs. Maximum levels of both fibroblast and leukocyte IFNs occurred prior to 24 h whereas maximum levels of immune IFN were not reached until after 72 h. The latter species of IFN was unstable at either pH 2 or 56°C whereas both the fibroblast and leukocyte IFNs were more stable under these conditions. Studies of cross-species protection between fibroblast and leukocyte IFNs indicate that the former was more protective for other species than the latter.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Lefkowitz, S. S., and Luna, V. E. R., Intervirology21 (1984) 221.

    Article  CAS  PubMed  Google Scholar 

  2. Lefkowitz, S. S., Talley, R. S., and Lefkowitz, D., Clin. Immun. News19 (1980) 1.

    Google Scholar 

  3. Babiuk, L. A., and Rouse, B. T., Infect. Immun.136 (1976) 1567.

    Article  Google Scholar 

  4. Johnson, H. M., Stanton, G. J., and Baron, S., Proc. Soc. exp. Biol. Med.154 (1977) 138.

    Article  CAS  PubMed  Google Scholar 

  5. Epstein, L. B., Tex. Rep. biol. Med.35 (1977) 42.

    CAS  PubMed  Google Scholar 

  6. Wheelock, E. F., Science149 (1965) 310.

    Article  CAS  PubMed  Google Scholar 

  7. Maehara, N., and Ho, M., Infect. Immun.15 (1977) 78.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Younger, J. S., and Salvin, S. B., J. Immun.111 (1973) 1914.

    Article  Google Scholar 

  9. Ahl, R., and Rump, A., Infect. Immun.14 (1976) 603.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Rosenquist, B. D., and Loan, R. W., Am. J. vet. Res.28 (1967) 619.

    CAS  PubMed  Google Scholar 

  11. Rosenquist, B. D., and Loan, R. S., Am. J. vet. Res.30 (1969) 1293.

    CAS  PubMed  Google Scholar 

  12. Fulton, R. W., and Rosenquist, B. D., Am. J. vet. Res.37 (1976) 1497.

    CAS  PubMed  Google Scholar 

  13. Cummins, J. M., and Rosenquist, B. D., Am. J. vet. Res.41 (1980) 161.

    CAS  PubMed  Google Scholar 

  14. Cummins, J. M., and Rosenquist, B. D., Am. J. vet. Res.43 (1982) 955.

    CAS  PubMed  Google Scholar 

  15. Fulton, R. W., and Pearson, N. J., Can. J. comp. Med.46 (1982) 100.

    CAS  PubMed  PubMed Central  Google Scholar 

  16. Jankowski, W. J., Davey, M. W., O'Malley, J. A., Sulkowski, E., and Carter, W. A., J. Virol.16 (1975) 1124.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Davey, M. W., Sulkowski, E., and Carter, W. A., Biochemistry15 (1976) 704.

    Article  CAS  PubMed  Google Scholar 

  18. Babiuk, L. A., and Rouse, B. T., Intervirology8 (1977) 250.

    Article  CAS  PubMed  Google Scholar 

  19. Carter, W. A., Davis, L. R., Jr, and Chadha, K. C., Molec. Pharmac.15 (1979) 685.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Supported in part by National Institutes of Health Biomedical Research Support Grant RR05773-08.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Luna, V.E.R., Luk, A.D.H., Tyring, S.K. et al. Properties of bovine interferons. Experientia 40, 1410–1412 (1984). https://doi.org/10.1007/BF01951916

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01951916

Key words

Navigation