Summary
This study was done in an attempt to elucidate some of the properties of bovine IFNs. Maximum levels of both fibroblast and leukocyte IFNs occurred prior to 24 h whereas maximum levels of immune IFN were not reached until after 72 h. The latter species of IFN was unstable at either pH 2 or 56°C whereas both the fibroblast and leukocyte IFNs were more stable under these conditions. Studies of cross-species protection between fibroblast and leukocyte IFNs indicate that the former was more protective for other species than the latter.
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Supported in part by National Institutes of Health Biomedical Research Support Grant RR05773-08.
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Luna, V.E.R., Luk, A.D.H., Tyring, S.K. et al. Properties of bovine interferons. Experientia 40, 1410–1412 (1984). https://doi.org/10.1007/BF01951916
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DOI: https://doi.org/10.1007/BF01951916