Experientia

, Volume 46, Issue 3, pp 290–292 | Cite as

Stress-induced increase in noradrenaline release in the rat hypothalamus assessed by intracranial microdialysis

  • H. Yokoo
  • M. Tanaka
  • T. Tanaka
  • A. Tsuda
Research Articles

Summary

The hypothalamic microdialysis of conscious rats was used to investigate the effects of immobilization stress (20 min) on extracellular noradrenaline(NA) levels. The stress significantly increased NA levels relative to basal efflux by 106% and this elevation continued for 40 min after release from stress.

Key words

In vivo microdialysis stress noradrenaline release hypothalamus high performance liquid chromatography rat 

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Copyright information

© Birkhäuser Verlag 1990

Authors and Affiliations

  • H. Yokoo
    • 1
  • M. Tanaka
    • 1
  • T. Tanaka
    • 1
  • A. Tsuda
    • 1
  1. 1.Department of PharmacologyKurume University School of MedicineKurume(Japan)

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