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Experientia

, Volume 46, Issue 3, pp 267–269 | Cite as

Metabolism of 3β-hydroxycholest-5-en-26-oic acid in hamsters

  • Y. Ayaki
  • E. Kok
  • N. B. Javitt
Research Articles
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Summary

Metabolism of 26-hydroxycholesterol to 3β-hydroxychol-5-en-24-oic acid and other C24-bile acids has been expected to occur by way of 3β-hydroxycholest-5-en-26-oic acid in studies in vitro. 3β-Hydroxycholest-5-en-26-oic acid was infused intravenously into bile fistula hamsters and the following C24-bile acids were identified: 3β-hydroxychol-5-en-24-oic acid, lithocholic acid, chenodeoxycholic acid, and a small amount of cholic acid.

Key words

3β-Hydroxycholest-5-en-26-oic acid bile acids hamsters metabolism 

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Copyright information

© Birkhäuser Verlag 1990

Authors and Affiliations

  • Y. Ayaki
    • 1
  • E. Kok
    • 2
  • N. B. Javitt
    • 2
  1. 1.Department of BiochemistryMedical School of Tottori UniversityYonago, Tottori(Japan)
  2. 2.Division of Hepatic DiseasesNew York University Medical CenterNew YorkUSA

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