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Antidiuretic hormone involvement in the release of α-melanocyte-stimulating hormone by hyperosmotic stimuli

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In the normal Wistar rat, the plasma α-MSH level was raised by hypertonic saline injection (as compared with control rats injected with isotonic saline). No such rise in α-MSH followed hypertonic saline administration in the Brattleboro (hereditary diabetes insipidus) animal (compared to isotonic saline injected controls). It is suggested that, in the rat, endogenous antidiuretic hormone is involved in the secretory response of the pars intermedia to osmotic stimuli.

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Authors and Affiliations

  1. Department of Physiology, Chelsea College, University of London, London, England

    A. Howe & K. S. Ray

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  1. A. Howe
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  2. K. S. Ray
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Howe, A., Ray, K.S. Antidiuretic hormone involvement in the release of α-melanocyte-stimulating hormone by hyperosmotic stimuli. Experientia 41, 1163–1165 (1985). https://doi.org/10.1007/BF01951709

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  • DOI: https://doi.org/10.1007/BF01951709

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