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Autophagy and lysosomal proteolysis in the liver

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Autophagy is defined as any process whereby cellular macromolecules destined for degradation gain access to the lysosomes. A review is presented on the physiological significance, mechanisms and regulation of autophagy in hepatocytes, concentrating on the issue of regulation. The article ends by discussing techniques available for future research.

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  1. Department of Biology, Division of Zoology, University of Oslo, Blindern, P.O. Box 1050, 0316, Oslo 3, Norway

    B. Grinde

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Grinde, B. Autophagy and lysosomal proteolysis in the liver. Experientia 41, 1089–1095 (1985). https://doi.org/10.1007/BF01951685

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