Schistosoma mansoni: Activity responses in vitro to praziquantel
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The effects of praziquantel, a novel antischistosomal compound, on the activity of adultSchistosoma mansoni (Liverpool strain) in vitro were investigated.
Worm activity was modified at all concentrations of praziquantel. High concentrations (above 0.5 μg/ml) produced rapid paralysis, whilst low concentrations of praziquantel stimulated worm activity. It is concluded that such activity modification could lead to worm displacement in vivo.
KeywordsActivity Modification Activity Response Schistosoma Praziquantel Schistosoma Mansoni
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