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Zeitschrift für Parasitenkunde

, Volume 58, Issue 2, pp 169–174 | Cite as

Schistosoma mansoni: Activity responses in vitro to praziquantel

  • C. J. Chavasse
  • M. C. Brown
  • D. R. Bell
Article

Summary

The effects of praziquantel, a novel antischistosomal compound, on the activity of adultSchistosoma mansoni (Liverpool strain) in vitro were investigated.

Worm activity was modified at all concentrations of praziquantel. High concentrations (above 0.5 μg/ml) produced rapid paralysis, whilst low concentrations of praziquantel stimulated worm activity. It is concluded that such activity modification could lead to worm displacement in vivo.

Keywords

Activity Modification Activity Response Schistosoma Praziquantel Schistosoma Mansoni 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • C. J. Chavasse
    • 1
  • M. C. Brown
    • 2
  • D. R. Bell
    • 1
  1. 1.Department of Tropical MedicineLiverpool School of Tropical MedicineLiverpoolUK
  2. 2.Bioengineering and Medical Physics UnitUniversity of LiverpoolLiverpoolUK

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