Skip to main content
SpringerLink
Log in

The influence of BrdU on interstitial cell differentiation in hydra

  • Specialia
  • Biologica
  • Published:
Experientia Aims and scope Submit manuscript

Summary

Exposure of hydra to 3.25×10−3 M BrdU selectively altered differentiation in the animal's pluripotent I-cell population. It is suggested, therefore, that this analog may represent a valid probe to analyze the controls regulating cellular differentiation in in vivo populations of pluripotent cells.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. W. J. Rutter, R. L. Pictet and P. W. Morris, A. Rev. Biochem.42, 601 (1973).

    Article  CAS  Google Scholar 

  2. R. D. Campbell and C. N. David, J. Cell Sci.16, 349 (1974).

    Article  CAS  PubMed  Google Scholar 

  3. W. F. Loomis and H. M. Lenhoff, J. exp. Zool.132, 555 (1956).

    Article  Google Scholar 

  4. M. H. Goyns and M. Stanisstreet, Roux' Arch.175, 87 (1974).

    Article  CAS  Google Scholar 

  5. C. N. David, Roux' Arch.171, 259 (1973).

    Article  Google Scholar 

  6. H. R. Bode, S. Berking, C. David, A. Gierer, H. Schaller and E. Trenkner, Roux' Arch.171, 269 (1973).

    Article  CAS  Google Scholar 

  7. H. R. Bode and K. M. Flick, J. cell Sci. 15 (1976).

  8. G. W. Snedecor, Statistical Methods. The Iowa State University Press, Ames 1956.

    Google Scholar 

  9. C. N. David and A. Gierer, J. cell Sci.16, 359 (1974).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biology, Case Western Reserve University, 44106, Cleveland, Ohio, USA

    Georgia E. Lesh-Laurie & W. N. Frank

Authors
  1. Georgia E. Lesh-Laurie
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. W. N. Frank
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Supported in part by a Brown-Hazen Grant from Research Corporation and an Institutional Grant from the American Cancer Society.

The authors gratefully acknowledge helpful discussions with Drs D. Brooks and M. Samuelson. Thanks are also extended to Dr Brooks for critically reading the manuscript.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lesh-Laurie, G.E., Frank, W.N. The influence of BrdU on interstitial cell differentiation in hydra. Experientia 33, 909–910 (1977). https://doi.org/10.1007/BF01951275

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01951275

Keywords

Search

Navigation