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The generation and identification of the hemolysin of Trypanosoma congolense

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Summary

The hemolytic activity of Trypanosoma congolense appears to be due to the presence of free fatty acids generated by the action of phospholipase A on endogenous phosphatidyl choline. Some lysolecithin also contributes to the lytic activity. Trypanosoma lewisi, being devoid of phospholipase A does not generate free fatty acids and is therefore non-hemolytic.

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Authors and Affiliations

  1. Department of Veterinary Microbiology and Immunology and of Chemistry, University of Guelph, Guelph, Ontario, Canada

    I. R. Tizard, W. L. Holmes, D. A. York & A. Mellors

Authors
  1. I. R. Tizard
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  2. W. L. Holmes
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  3. D. A. York
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  4. A. Mellors
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Additional information

This research was supported by the International Development Research Center.

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Tizard, I.R., Holmes, W.L., York, D.A. et al. The generation and identification of the hemolysin of Trypanosoma congolense. Experientia 33, 901–902 (1977). https://doi.org/10.1007/BF01951271

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  • DOI: https://doi.org/10.1007/BF01951271

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