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Experientia

, Volume 33, Issue 7, pp 873–874 | Cite as

Effect and fate of intravenously administered porphobilin in rats

  • C. A. Pierach
  • L. Guidon
  • Z. J. Petryka
  • H. R. Baur
  • C. J. Watson
Specialia Chimica, Biochimica

Summary

It rats after i.v. prophobilin, blood pressure and pulse rate remained stable, the animals were calm and moved freely with no symptoms or signs of nervous effect. Prophobilin was rapidly excreted in the urine.

Keywords

Blood Pressure Pulse Rate Nervous Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    D. Shemin, I. M. London and O. Rittenberg, J. biol. Chem.173, 799 (1948).Google Scholar
  2. 2.
    S. Granick and D. Mauzerall, J. Biol. Chem.232, 119 (1958).Google Scholar
  3. 3.
    E. L. B. Dresel and J. E. Falk, Biochem. J.63, 80 (1956).PubMedGoogle Scholar
  4. 4.
    C. S. Russell, J. theor. Biol.47, 145 (1974).CrossRefPubMedGoogle Scholar
  5. 5.
    R. B. Frydman, A. Valasinas and B. Frydman, Enzyme16, 151 (1973).PubMedGoogle Scholar
  6. 6.
    L. Bogorad, Science121, 818 (1955).Google Scholar
  7. 7.
    L. Bogorad, J. biol. Chem.233, 501 (1958).PubMedGoogle Scholar
  8. 8.
    B. Frydman, R. B. Frydman, A. Valasinas, E. S. Levy and G. Feinstein, Phil. Trans. Soc. London273 (924), 137 (1976).Google Scholar
  9. 9.
    M. Akhtar, M. M. Aboud, G. Barnard, P. Jordan and Z. Z. Aman, Phil. Trans. R. Soc. London273 (924), 117 (1976).Google Scholar
  10. 10.
    C. J. Watson, G. J. Dhar, I. Bossenmaier, R. Cardinal and Z. J. Petryka, Ann. intern. Med.79, 80 (1973).PubMedGoogle Scholar
  11. 11.
    D. S. Feldman, R. D. Levere, J. S. Lieberman, R. A. Cardinal and C. J. Watson, Proc. nat. Acad. Sci. USA,68, 383 (1971).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • C. A. Pierach
    • 1
  • L. Guidon
    • 1
  • Z. J. Petryka
    • 1
  • H. R. Baur
    • 1
  • C. J. Watson
    • 1
  1. 1.Northwestern HospitalUniversity of Minnesota Medical Research UnitMinneapolisUSA

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