Summary
Structures of several hydroxylysine-containing glycopeptides derived from the body wall of the sea cucumber have been determined. The glycosylated hydroxylysines were all the Y positions of Gly-X-Y triplets. They are thought to be distributed throughout the peptide chain, in contrast to vertebrate skin collagens. One glycopeptide demonstrated the existence of the sequence Gly-Gly-Hyp in invertebrates for the first time.
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Acknowledgments. The authors wish to express their gratitude to Dr. R. Hayashi of Kyoto University for a generous gift of carboxypeptidase Y. This study was supported in part by a scientific research grant from the Ministry of Education, Science and Culture of japan.
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Isemura, M., Ikenaka, T. Collagen glycopeptides from the sea cucumber Stichopus japonicus. Experientia 33, 871–872 (1977). https://doi.org/10.1007/BF01951252
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DOI: https://doi.org/10.1007/BF01951252