Skip to main content
Log in

Collagen glycopeptides from the sea cucumber Stichopus japonicus

  • Specialia
  • Chimica, Biochimica
  • Published:
Experientia Aims and scope Submit manuscript

Summary

Structures of several hydroxylysine-containing glycopeptides derived from the body wall of the sea cucumber have been determined. The glycosylated hydroxylysines were all the Y positions of Gly-X-Y triplets. They are thought to be distributed throughout the peptide chain, in contrast to vertebrate skin collagens. One glycopeptide demonstrated the existence of the sequence Gly-Gly-Hyp in invertebrates for the first time.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. R. G. Spiro, in: Glycoproteins, vol. 5, p. 964, Ed. A. Gottschalk. BBA Library, Elsevier, Amsterdam 1972.

    Google Scholar 

  2. R. D. Marshall, A. Rev. Biochem.41, 673 (1972).

    Article  CAS  Google Scholar 

  3. R. G. Spiro, Adv. Protein Chem.27, 350 (1973).

    Google Scholar 

  4. P. M. Gallop and M. A. Paz, Physiol. Rev.55, 418 (1975).

    Article  CAS  PubMed  Google Scholar 

  5. M. Isemura, R. K. Zahn and K. Schmid, Biochem. J.131, 509 (1973)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. M. Isemura, T. Ikenaka and Y. Matsushima, J. Biochem., Tokyo74, 11 (1973).

    Article  CAS  PubMed  Google Scholar 

  7. M. Isemura and T. Ikenaka, Biochim. biophys. Acta404 11 (1975).

    Article  Google Scholar 

  8. M. Isemura, T. Ikenaka, T. Mega and Y. Matsushima, Biochem. biophys. Res. Comm.57, 751 (1974).

    Article  CAS  PubMed  Google Scholar 

  9. F. Sanger and H. Tuppy, Biochem. J.49, 463 (1951).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. R. Hayashi, S. Moore and W. H. Stein, J. biol. Chem.248, 2296 (1973).

    Article  CAS  PubMed  Google Scholar 

  11. P. H. Morgan, H. G. Jacobs, J. P. Segrest and L. W. Cunningham, J. biol. Chem.245, 5042 (1970).

    Article  CAS  PubMed  Google Scholar 

  12. J. H. Aguilar, H. G. Jacobs, W. T. Butler and L. W. Cunningham, J. biol. Chem.248, 5106 (1973).

    Article  CAS  PubMed  Google Scholar 

  13. N. A. Kefalides, Biochem. biophys. Res. Comm.47, 1151 (1972).

    Article  CAS  PubMed  Google Scholar 

  14. P. P. Fietzek and J. Rauterberg, FEBS Lett49, 365 (1975).

    Article  CAS  PubMed  Google Scholar 

  15. P. P. Fietzek and K. Kühn, Mol. cell Biochem.8, 141 (1975).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Acknowledgments. The authors wish to express their gratitude to Dr. R. Hayashi of Kyoto University for a generous gift of carboxypeptidase Y. This study was supported in part by a scientific research grant from the Ministry of Education, Science and Culture of japan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Isemura, M., Ikenaka, T. Collagen glycopeptides from the sea cucumber Stichopus japonicus. Experientia 33, 871–872 (1977). https://doi.org/10.1007/BF01951252

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01951252

Keywords

Navigation