Summary
Circular dichroism and absorption spectra of ferrihemoglobin were shown to be altered upon binding with poly-L-lysine at alkaline pH. When ferrihemoglobin immobilized to Sepharose gel was treated with poly-L-lysine, hemoglobin subunits were released from the gel. These results suggest that ferrihemoglobin was dissociated into subunits by poly-L-lysine.
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We thank Dr A. Ichihara and K. Aki for their valuable discussions and encouragement during the course of these studies.
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Imai, K., Yoshimura, T. Evidence for dissociation of ferrihemoglobin by poly-L-lysine. Experientia 35, 1003–1005 (1979). https://doi.org/10.1007/BF01949906
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DOI: https://doi.org/10.1007/BF01949906