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Regulation of testosterone production in fetal testicular cells: effect of androgens

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Summary

Pre-incubation of dispersed testicular cells from 18-day-old mouse fetuses in presence of testosterone or dihydrotestosterone resulted in a significant decrease of the hCG-stimulated testosterone production. These results suggest that during late fetal life testosterone production may be inhibited by an ultra-short loop feedback of androgens.

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Authors and Affiliations

  1. Groupe de Recherches sur l'Endocrinologie de la Reproduction, U. 166 INSERM, Maternité Port-Royal, 123, Bld Port-Royal, F-75014, Paris, France

    G. Pointis, M. T. Latreille & L. Cedard

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  1. G. Pointis
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  2. M. T. Latreille
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  3. L. Cedard
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Pointis, G., Latreille, M.T. & Cedard, L. Regulation of testosterone production in fetal testicular cells: effect of androgens. Experientia 40, 756–757 (1984). https://doi.org/10.1007/BF01949763

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  • DOI: https://doi.org/10.1007/BF01949763

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