Skip to main content
SpringerLink
Log in

Atypical base composition of foldback DNA

  • Specialia
  • Published:
Experientia Aims and scope Submit manuscript

Summary

Salmon, calf and human foldback DNAs all exhibited hypermethylation, reduced adenine plus thymine content and an excess of adenine over thymine when compared with their respective native DNAs. The only unusual feature of the base composition of wheat germ foldback DNA was the excess of thymine over adenine.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. R.J. Britten and J. Smith, Carnegie Inst. Wash. Yearb.68, 378 (1970).

    Google Scholar 

  2. D.A. Wilson and C.A. Thomas, Jr, J. molec. Biol.84, 115 (1974).

    Article  CAS  PubMed  Google Scholar 

  3. C.A.G. Haasnoot, J.H.J. den Hartog, J.F.M. de Rooij, J.H. van Boom and C. Altona, Nucleic Acids Res.8, 169 (1980).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. N. Hardman, A.J. Bell and A. McLachlan, Biochim. biophys. Acta564, 372 (1979).

    Article  CAS  PubMed  Google Scholar 

  5. M. Brahic and M.J. Fraser, Biochim. biophys. Acta240, 23 (1971).

    Article  CAS  PubMed  Google Scholar 

  6. C.W. Schmid, J.E. Manning and N. Davidson, Cell5, 159 (1975).

    Article  CAS  PubMed  Google Scholar 

  7. P.J. Dott, C.R. Chuang and G.F. Saunders, Biochemistry15, 4120 (1976).

    Article  CAS  PubMed  Google Scholar 

  8. H.J. Lin and C.L.H. Lee, Analyt. Biochem.96, 144 (1979).

    Article  CAS  PubMed  Google Scholar 

  9. H.L. Klein and S.K. Welch, Nucleic Acids Res.8, 4651 (1980).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. T.J. Kelly, Jr, and H.O. Smith, J. molec. Biol.51, 393 (1970).

    Article  CAS  PubMed  Google Scholar 

  11. A.M. Maxam and W. Gilbert, Proc. natl Acad. Sci. USA70, 3581 (1973).

    Article  PubMed  PubMed Central  Google Scholar 

  12. W.R. Jelinek, J. molec. Biol.115, 591 (1977).

    Article  CAS  PubMed  Google Scholar 

  13. W.R. Jelinek, G. Molloy, R. Fernandez-Munoz, M. Salditt and J.E. Darnell, J. molec. Biol.82, 361 (1974).

    Article  CAS  PubMed  Google Scholar 

  14. D. Drabovsky, T.L.J. boehm and W. Kresis, Biochim. biophys. Acta563, 28 (1979).

    Article  Google Scholar 

  15. M.H. Schneiderman and D. Billen, Biochim. biophys. Acta308, 352 (1973).

    Article  CAS  PubMed  Google Scholar 

  16. G.R. Wyatt, in: The Nucleic Acids, vol. 1, p. 243. Ed. E. Chargaff and J.N. Davidson. Academic Press, New York 1955.

    Google Scholar 

  17. G.H. Beaven, in: The Nucleic Acids, vol. 1, p. 493. Ed. E. Chargaff and J.N. Davidson. Academic Press, New York 1955.

    Google Scholar 

  18. A. Razin and J. Sedat, Analyt. Biochem.77, 370 (1977).

    Article  CAS  PubMed  Google Scholar 

  19. J.W. Drake and R.H. Baltz, A. Rev. Biochem.45, 11 (1976).

    Article  CAS  Google Scholar 

  20. J.H. Taylor, in: Molecular Genetics, part 3, p. 89. Ed. J.H. Taylor. Academic Press, New York 1979.

    Chapter  Google Scholar 

  21. J.E. Gill, J.A. Mazrimas and C.C. Bishop, Jr, Biochim. biophys. Acta335, 330 (1974).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, Queen Mary Hospital Compound, University of Hong Kong, Hong Kong, Hong Kong

    D. H. S. Lee & H. J. Lin

Authors
  1. D. H. S. Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. J. Lin
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

This work was supported by grants from the Committee on Higher Degrees and Research Grants and the Department of Pathology, University of Hong Kong.

This study was carried out in partial fulfillment of the requirements of the University of Hong Kong for the degree of Doctor of Philosophy.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lee, D.H.S., Lin, H.J. Atypical base composition of foldback DNA. Experientia 38, 344–346 (1982). https://doi.org/10.1007/BF01949382

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01949382

Keywords

Search

Navigation