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Ferredoxin reductase catalyzes styrene oxidation to styrene oxide

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Summary

The flavoprotein ferredoxin reductase catalyzed the oxidation of styrene to styrene oxide in the presence of NADPH. This reaction was inhibited by the addition of catalase and superoxide dismutase. The addition of the nonheme iron protein ferredoxin partially inhibited styrene oxidation. H2O2 was also able to catalyze this reaction when added to the enzyme in the absence of NADPH.

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Authors and Affiliations

  1. Istituto di Ricerche Farmacologiche ‘Mario Negri’, Via Eritrea 62, I-20157, Milano, Italy

    G. Belvedere, D. Blezza & L. Cantoni

Authors
  1. G. Belvedere
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  2. D. Blezza
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  3. L. Cantoni
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Additional information

Acknowledgments. This work was supported by C.N.R. (National Research Council), Rome, Italy contract No. 79.03197.04.

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Belvedere, G., Blezza, D. & Cantoni, L. Ferredoxin reductase catalyzes styrene oxidation to styrene oxide. Experientia 38, 306–307 (1982). https://doi.org/10.1007/BF01949357

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