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Ultrasound guided fine-needle biopsies in pancreatic and hepatic neoplasms

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Abstract

Two hundred patients underwent ultrasound-guided percutaneous fine-needle aspiration biopsies of hepatic and pancreatic space-occupying lesions. In addition to the cytologic smear preparations (100%), tissue fragments and cores suitable for histological evaluation were obtained from aspirated samples in 84% of specimens from hepatic targets (n=130) and in 61 % of specimens from pancreatic lesions (n=70). The prevalence of malignant disease was 78.5% in the liver study group and 74.3% in the patients undergoing pancreatic biopsies. The overall accuracy rate of cytohistologic readings for malignancy was 94.6% in liver biopsies and 92.9% in pancreatic biopsies with a high predictive value of positive results of 98% and 100%, respectively, and a less satisfying predictive value of negative results of 83.9% and 77.3%, respectively. Two false-positive diagnoses were encountered in the evaluation of cytologic smear preparations of hepatic aspirations. No serious complications occurred with the biopsy procedure. Ultrasound-guided fine-needle biopsy is recommended as a safe and reliable method for cytohistological confirmation of suspected hepatic and pancreatic malignancy.

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Authors and Affiliations

  1. Department of Medicine, Gastroenterology Unit, Philipps University, D-3550, Marburg/Lahn, West Germany

    Wolf B. Schwerk, Hans-K. Dürr & Paul Schmitz-Moormann

  2. Department of Pathology, Philipps University of Marburg/Lahn, West Germany

    Wolf B. Schwerk, Hans-K. Dürr & Paul Schmitz-Moormann

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  1. Wolf B. Schwerk
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  2. Hans-K. Dürr
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  3. Paul Schmitz-Moormann
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Schwerk, W.B., Dürr, HK. & Schmitz-Moormann, P. Ultrasound guided fine-needle biopsies in pancreatic and hepatic neoplasms. Gastrointest Radiol 8, 219–225 (1983). https://doi.org/10.1007/BF01948123

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  • DOI: https://doi.org/10.1007/BF01948123

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