Abstract
Potassium permeability was monitored in human sweat glands and rat submandibular glands. Acetylcholine increased permeability in both tissues and the responses consisted of transient, calcium-independent and sustained, calcium-dependent components. Amiloride, a drug which inhibits Na+−H+ countertransport, impaired the regulation of potassium permeability in sweat glands but not in the submandibular gland. It is suggested that the stimulus-permeability coupling process in the sweat gland may be sensitive to the lowering of internal pH.
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Wilson, S.M., Pediani, J.D., Jenkinson, D.M. et al. Amiloride impairs the cholinergic regulation of potassium permeability in the human sweat gland but not in the rat submandibular gland. Experientia 48, 1115–1117 (1992). https://doi.org/10.1007/BF01948001
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DOI: https://doi.org/10.1007/BF01948001