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Rabbit immunization to xenogeneic red blood cells following anterior eye chamber inoculation

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Summary

Inoculation of human red blood cells (HRBC) into the anterior chamber of the eye (AC) of rabbits effectively stimulazed systemic antibody production. Intraocular (i.o.) inoculation was observed to be more effective a route of immunization than i.v. or i.m. inoculation of antigen. These results contradict the accepted belief that the AC is an immunologically privileged site in the body.

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Author notes

  1. M. W. Dennis

    Present address: Primate Research Institute, New Mexico State University, P.O. Box 1027, 88330, Holloman AFB, NM, USA

Authors and Affiliations

  1. Department of Microbiology, Weber State College, Ogden, Utah, USA

    M. W. Dennis

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  1. M. W. Dennis
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Dennis, M.W. Rabbit immunization to xenogeneic red blood cells following anterior eye chamber inoculation. Experientia 40, 271–273 (1984). https://doi.org/10.1007/BF01947577

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  • DOI: https://doi.org/10.1007/BF01947577

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