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Cytoskeletal filaments of heart conducting system localized by antibody against a 55,000 dalton protein

Experientia volume 34, pages 792–794 (1978)Cite this article

Summary

Cow heart conducting cells characteristically contain cytoplasmic intermediate-sized filaments. We report here the preparation of a specific antibody to a 55,000 dalton protein of isolated cow Purkinje fibres. Confirmation has been obtained that these filaments consist of the 55,000 dalton protein, using the indirect immunofluorescence technique. Crossreaction is seen with vascular endothelium and smooth muscle cells of various origin, suggesting close identity of different types of intermediate-sized filaments.

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Affiliations

  1. Department of Anatomy, University of Umeå, S-90187, Umeå, (Sweden)

    A. Eriksson, L. -E. Thornell & T. Stigbrand

  2. Department of Physiological Chemistry, University of Umeå, S-90187, Umeå, (Sweden)

    A. Eriksson, L. -E. Thornell & T. Stigbrand

Authors
  1. A. Eriksson
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  2. L. -E. Thornell
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  3. T. Stigbrand
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Eriksson, A., Thornell, L.E. & Stigbrand, T. Cytoskeletal filaments of heart conducting system localized by antibody against a 55,000 dalton protein. Experientia 34, 792–794 (1978). https://doi.org/10.1007/BF01947331

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  • DOI: https://doi.org/10.1007/BF01947331

Keywords

  • Smooth Muscle
  • Muscle Cell
  • Smooth Muscle Cell
  • Specific Antibody
  • Vascular Endothelium