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Mise en évidence de l'excrétion urinaire d'antigènes de la membrane basale glomerulaire (MBG) dans l'urine de 3 rongeurs (rat, souris et cobaye)

Evidence of urinary glomerular basement membrane (GBM) antigens excretion in 3 rodents (rat, mouse and guinea-pig)

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Summary

Immunodiffusion technique, with rabbits antibodies against rat glomerular basement membrane (GBM), permits to evidence the presence of GBM antigens into normal urines of 3 rodents (rat, mouse and guinea-pig). These results confirm the earlier works in human and rabbit urines and show the antigenic communauty existing between the 3 rodents GBM, since we can evidence antigens of 3 different mammals with the same antibody. The origin and the nature of this patterns and the signification of this presence into mammalian urines are discussed.

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Author notes

  1. Y. Piquet & Y. Mesnier

    Present address: Service d'Immunochimie, Centre de Transfusion Sanguine de Bordeaux, F-33000, Bordeaux

  2. J. Montoriol

    Present address: Service de Clinique Néphrologique, Hôpital Pellegrin, F-33000, Bordeaux

Authors and Affiliations

  1. Laboratoire de Pharmacodynamie, Faculté de Pharmacie, 91, rue Leyteire, F-33 000, Bordeaux, (France)

    J. Cambar, Y. Piquet, J. Montoriol & Y. Mesnier

Authors
  1. J. Cambar
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  2. Y. Piquet
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  3. J. Montoriol
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  4. Y. Mesnier
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Additional information

Nous remercions sincèrement le Docteur Mahieu (Laboratoire de Clinique et Séméiologie Médicales, Institut de Médecine de l'Hôpital Universitaire de Bavière à Liège, Belgique) de l'aide précieuse qu'il a bien voulu nous accorder.

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Cambar, J., Piquet, Y., Montoriol, J. et al. Mise en évidence de l'excrétion urinaire d'antigènes de la membrane basale glomerulaire (MBG) dans l'urine de 3 rongeurs (rat, souris et cobaye). Experientia 34, 747–748 (1978). https://doi.org/10.1007/BF01947300

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  • DOI: https://doi.org/10.1007/BF01947300

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