Experientia

, Volume 34, Issue 6, pp 745–746 | Cite as

Bayliss myogenic response in the isolated ductus arteriosus of guinea-pig and rabbit fetuses

  • V. Smieško
  • M. Kriška
  • V. Kovalčík
Specialia

Summary

Isolated ductus arteriosus responds by marked constriction to increases in perfusion pressure. If, however, these increases exceed 90 mm Hg-130 mm Hg, the vessel suddenly dilates and its responsiveness becomes depressed. The importance of these findings in postnatal closure of ductus arteriosus is discussed.

Keywords

Perfusion Pressure Myogenic Response Rabbit Fetus Marked Constriction Postnatal Closure 

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Copyright information

© Birkhäuser-Verlag 1978

Authors and Affiliations

  • V. Smieško
    • 1
    • 2
  • M. Kriška
    • 1
    • 2
  • V. Kovalčík
    • 1
    • 2
  1. 1.Institute of Normal and Pathological PhysiologySlovak Academy of Sciences(Czechoslovakia)
  2. 2.Department of PharmacologyKomensky University Medical SchoolBratislava(Czechoslovakia)

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