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Effect of chronic alloxan diabetes and insulin administration on intestinal brush border enzymes

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Summary

Brush border sucrase and lactase activities are significantly elevated in alloxan-induced chronic diabetes and are restored to control levels after insulin treatment. Alkaline phosphatase and Mg-ATPase levels remain unchanged in diabetes, compared to a control group. Insulin treatment alone to control animals also led to enhanced activities of these enzymes.

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Mahmood, A., Pathak, R. & Agarwal, N. Effect of chronic alloxan diabetes and insulin administration on intestinal brush border enzymes. Experientia 34, 741–742 (1978). https://doi.org/10.1007/BF01947295

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