Summary
The ability of cells to adhere to a substratum was altered by treatment with trypsin but was restored after a 1.5-h culture. A concomitant incorporation of [3H] leucine and [4C] glucosamine in the trypsin-sensitive cell surface glycoproteins was observed and almost reached a plateau within 1.50 h following the treatment with trypsin.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Acknowledgment. This work was supported by grants from INSERM, ATP No. 43-76-75.
M.F. Collins, in: Neoplasia and Cell Differentiation, p. 234. B.V. Sherbet, 1974.
G.L. Nicolson, Int. Rev. Cytol.39, 90 (1974).
D.R. Critchley, J.A. Wyker and P.O. Hynes, Biochem. biophys. Acta436, 335 (1976).
M. Aubery and R. Bourrillon, Cell Differentiation.5, 27 (1976).
O.H. Lowry, N.J. Rosenbrough, A.L. Farr and R.J. Randall, J. biol. Chem.193, 265 (1951).
N.G. Maroudas, Exp. Cell Res.81, 104 (1973).
G.R. Martin and H. Rubin, Exp. Cell Res.85, 319 (1974).
R.C. Hughes, in: Membranes Glycoproteins. p. 257. Butterworths, London 1976.
F. Moreau and R. Bourrillon, Biochem. biophys. Acta443, 375 (1976).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Vernay, M., Cornic, M., Aubery, M. et al. Relationship between regeneration of cell surface glycoproteins in trypsin-treated chick embryo fibroblasts and cell adhesion to the substratum. Experientia 34, 736–737 (1978). https://doi.org/10.1007/BF01947292
Issue Date:
DOI: https://doi.org/10.1007/BF01947292