, Volume 34, Issue 6, pp 731–733 | Cite as

HCO 3 -ATPase activity distribution in rat liver cell fractions prepared by zonal centrifugation

  • K. T. Izutsu
  • I. A. Slegel
  • E. A. Smuckler


Plasma membrane sheets prepared by zonal centrifugation of a premicrosomal pellet obtained from a rat liver homogenate are devoid of HCO 3 -ATPase activity. Since the microsomal fraction is also lacking in this ATPase activity, it can be concluded that the HCO 3 -ATPase is not involved in the secretion of HCO 3 into bile.


Plasma Membrane Centrifugation Liver Cell ATPase Activity Cell Fraction 
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Copyright information

© Birkhäuser-Verlag 1978

Authors and Affiliations

  • K. T. Izutsu
    • 1
    • 2
  • I. A. Slegel
    • 1
    • 2
  • E. A. Smuckler
    • 1
    • 2
  1. 1.Department of Oral Biology, School of DentistryUniversity of WashingtonSeattle(USA)
  2. 2.Department of PathologyUniversity of California School of MedicineSan Francisco(USA)

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