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The site of 25-hydroxycholecalciferol stimulated protein synthesis in the rat kidney

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Summary

Autoradiographs of the kidneys of rachitic rats dosed in vivo with 250 pmoles 25-hydroxycholecaliferol (25-OHD3) and3H-leucine showed increased grain counts in portions of proximal renal tubules. On incubation of kidney slices the synthesis of only 1 cytosol protein was found to be stimulated by the steroid. On disc gel electrophoresis it had the characteristics of renal calcium binding protein.

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References

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Author notes

  1. M. Cochran

    Present address: Department of Medicine, Flinders Medical Centre, 5042, Bedford Park, (South Australia)

Authors and Affiliations

  1. University Department of Medicine, Renal Unit, Royal Hospital, S1 3SR, Sheffield, (England)

    M. Cochran

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  1. M. Cochran
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Cochran, M. The site of 25-hydroxycholecalciferol stimulated protein synthesis in the rat kidney. Experientia 34, 719–720 (1978). https://doi.org/10.1007/BF01947279

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  • DOI: https://doi.org/10.1007/BF01947279

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