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Short-term effects of colcemid on the rapid axonal transport of proteins in the optic pathway of chick embryos

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Riassunto

La somministrazione endoculare di piccole dosi di Colcemid in embrioni di pollo al 13° e al 18° giorno di incubazione diminuisce la sintesi proteica nella retina. Pur in misura diversa, i due farmaci bloccano il trasporto assonico di proteine dalle cellule gangliari retiniche al tetto ottico. Anche nell'embrione quindi il trasporto assonico dipende dalla integrità dei microtubuli neuronali.

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Authors and Affiliations

  1. Istituto di Istologia ed Embriologia generale, Corso M. d'Azeglio 52, I-10126, Torino, (Italy)

    P. C. Marchisio, M. Aglietta & D. Rigamonti

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  1. P. C. Marchisio
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  2. M. Aglietta
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  3. D. Rigamonti
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Additional information

This work was supported by Consiglio Nazionale delle Ricerche (C.N.R.), Rome, Italy.

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Marchisio, P.C., Aglietta, M. & Rigamonti, D. Short-term effects of colcemid on the rapid axonal transport of proteins in the optic pathway of chick embryos. Experientia 29, 1126–1127 (1973). https://doi.org/10.1007/BF01946759

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