Résumé
Une proportion non négligeable de disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP) et de disodium dichloromethylenediphosphonate (Cl2MDP) peut être absorbée au niveau de l'ileum de poulet. L'absorption du Cl2MDP est significativement supérieure à celle de l'EHDP.
References
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Both14C-EHDP (disodium ethane-1-hydroxy-1,1-dophosphonate and14C-Cl2MDP (disodium dichloromethylene diphosphonate) were provided by the Procter and Gamble Company, Cincinnati, Ohio, USA. Specific activity:14C-EHDP 1.97 mCi/mmole,14C-Cl2MDP 0.55 mCi/mmole.
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Acknowledgements. We thank MissLinda Senior for her skillful technical assistance. This work has been supported by the Procter and Gambel Company, by the US National Institute of Health (Grant No. AM 07256) and by the Swiss National Research Fund (Grant No. 3.326.70 Sr). R. H. W. was supported, in part, by the John Simon Guggenheim Foundation.
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Wasserman, R.H., Bonjour, J.P. & Fleisch, H. Ileal absorption of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP) and disodium dichloromethylene diphosphonate (Cl2 MDP) in the chick. Experientia 29, 1110–1111 (1973). https://doi.org/10.1007/BF01946749
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DOI: https://doi.org/10.1007/BF01946749