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Differential expression and dosage compensation of theα-amylase gene inDrosphila miranda

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Summary

Theα-amylase gene ofDrosophila miranda is located on the X2-and on the neo-Y-chromosome, both developing sex chromosomes. Crosses between strains carrying different electrophoretically distinguishable alleles of theα-amylase gene were performed. Females of the F1 offspring showed the expected heterozygosity, while the males proved to be hemizygous for this locus. Only the gene on the X2-chromosome is expressed, whereas the corresponding gene on the neo-Y-chromosome is not. Estimates of theα-amylase activity in crude homogenates of male and female flies suggest strongly that theα-amylase gene is dosage compensated inD. miranda. In contrast to this situation, in all otherDrosophila species theα-amylase allele is autosomal and hence not dosage compensated.

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References

  1. MacKnight, R.H., Genetics24 (1939) 180.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Steinemann, M., Chromosoma86 (1982) 59.

    Article  CAS  PubMed  Google Scholar 

  3. Strobel, E., Pelling, C., and Arnheim, N., Proc. natn. Acad. Sci.75 (1978) 931.

    Article  CAS  Google Scholar 

  4. Muller, H.J., Genetics3 (1918) 422.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Muller, H.J., Am. Nat.66 (1932).

  6. Steinemann, M., Pinsker, W., and Sperlich, D., Chromosoma91 (1984) 46.

    Article  Google Scholar 

  7. Doane, W.W., Treat-Clemons, L.G., Gemmill, R.M., Levy, J.N., Hawley, S.A., Buchberg, A.M., and Paigen, K., in: Isozymes: Current Topics in Biological and Medical Research, vol. 9, p. 63. Liss, A. R., Inc., New York 1984.

    Google Scholar 

  8. Davis, B.J., Ann. N.Y. Acad. Sci.121 (1964) 404.

    Article  CAS  PubMed  Google Scholar 

  9. Harris, H., and Hopkinson, D.A., in: Handbook of Enzyme Electrophoresis in Human Genetics. Northholland publishing company, Amsterdam 1976.

    Google Scholar 

  10. Bradford, M.M., Analyt. Biochem.72 (1976) 248.

    Article  CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Abt. für Entwicklungsbiologie and Genetik, Universität Salzburg, E.-Klotz-Str. 11, A-5411, Salzburg, Austria

    M. Steinemann, S. Steinemann & J. Fakler

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  1. M. Steinemann
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  2. S. Steinemann
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  3. J. Fakler
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Additional information

Acknowledgments. We would like to thank Betty C. Moore, for the kind supply ofD. miranda strains. For the help and advice in the electrophoretic separation of theα-amylase variants we are indebted to Dr W. Pinsker. This work was supported by a grant from the Fonds zur Förderung der wissenschaftlichen Forschung, P5413 (Austria).

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Steinemann, M., Steinemann, S. & Fakler, J. Differential expression and dosage compensation of theα-amylase gene inDrosphila miranda. Experientia 42, 577–579 (1986). https://doi.org/10.1007/BF01946711

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