, Volume 33, Issue 5, pp 603–604 | Cite as

Phalloidin poisoning of isolated hepatocytes: Inhibition of protein synthesis

  • E. Gravela
  • G. Poli


Phalloidin added to isolated hepatocytes inhibits amino acid incorporation into protein. Inhibition is very strong with 20 μg/ml phalloidin and occurs after a lag period of about 30 min. After this period, poisoned hepatocytes also show morphological changes in their plasma membrane.


Plasma Membrane Protein Synthesis Morphological Change Phalloidin Acid Incorporation 
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Copyright information

© Birkhäuser-Verlag 1977

Authors and Affiliations

  • E. Gravela
    • 1
  • G. Poli
    • 1
  1. 1.Istituto di Patologia generale dell'Università di TorinoTorino(Italy)

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