, Volume 40, Issue 9, pp 996–997 | Cite as

Makisterone A: Its distribution and physiological role as the molting hormone of true bugs

  • T. J. Kelly
  • J. R. Aldrich
  • C. W. Woods
  • A. B. Borkovec


Makisterone A, a 28-carbon (C-24 alkyl) hexahydroxy steroid, has been identified by mass spectrometry as the major ecdysteroid in last-stage larvae of the large milkweed bug,Oncopeltus fasciatus, a phytophagous hemipteran. Similarly, it is a major molting hormone in 2 phytophagous and 1 predacious species of Hemiptera belonging to the group, Pentatomomorpha. It is not, however, a major ecdysteroid in another group of Hemiptera, the Cimicomorpha, where 1 predacious and 2 hematophagous species contain ecdysone and 20-hydroxyecdysone as their major molting hormones.

Key words

Milkweed bug Oncopeltus fasciatus makisterone A molting hormone ecdysteroid 


  1. 2.
    Hetru, C., and Horn, D. H. S., in: Progress in Ecdysone Research, p. 13. Ed. J. A. Hoffmann. Elsevier/North Holland, Amsterdam 1980.Google Scholar
  2. 3.
    Kaplanis, J. N., Dutky, S. R., Robbins, W. E., Thompson, M. J., Lindquist, E. L., Horn, D. H. S., and Galbraith, M. N., Science190 (1975) 681.Google Scholar
  3. 4.
    Kelly, T. J., Woods, C. W., Redfern, R. E., and Borkovec, A. B., J. exp. Zool.218 (1981) 127.Google Scholar
  4. 5.
    Aldrich, J. R., Kelly, T. J., and Woods, C. W., J. Insect Physiol.28 (1982) 857.Google Scholar
  5. 6.
    Gibson, J. M., Majumder, M. S. I., Mendis, A. H. W., and Rees, H. H., Archs Insect Biochem. Physiol.1 (1983) 105.Google Scholar
  6. 7.
    Koolman, J., Insect Biochem.12 (1982) 225.Google Scholar
  7. 8.
    Aldrich, J. R., Svoboda, J. A., and Thompson, M. J., J. exp. Zool.218 (1981) 133.Google Scholar
  8. 9.
    Dorn, A., and Buhlman, K.-J., Experientia38 (1982) 367.Google Scholar
  9. 10.
    Borst, D. W., and O'Connor, J. D., Steroids24 (1974) 637.Google Scholar
  10. 11.
    Gilbert, L. I., Goodman, W., and Bollenbacher, W. E., Int. Rev. Biochem.14 (1977) 1.Google Scholar
  11. 12.
    Morgan, E. D., and Poole, C. F., J. Chromat.116 (1976) 333.Google Scholar
  12. 13.
    Aldrich, J. R., unpublished results.Google Scholar
  13. 14.
    Jishba, J., Herout, V., and Sorm, F., Tetrahedron Lett.18 (1967) 1689.Google Scholar
  14. 15.
    Steel, C. G. H., Bollenbacher, W. E., Smith, S. L., and Gilbert, L. I., J. Insect Physiol.28 (1982) 519.Google Scholar
  15. 16.
    Wigglesworth, V. B., J. exp. Biol.32 (1955) 649.Google Scholar
  16. 17.
    Thompson, M. J., Kaplanis, J. N., Robbins, W. E., and Svoboda, J. A., Adv. Lipid Res.11 (1973) 219.Google Scholar
  17. 18.
    Svoboda, J. A., Kaplanis, J. N., Robbins, W. E., and Thompson, M. J., A. Rev. Ent.20 (1975) 205.Google Scholar
  18. 19.
    Svoboda, J. A., Thompson, M. J., Robbins, W. E., and Kaplanis, J. N., Lipids13 (1978) 742.Google Scholar
  19. 20.
    Rees, H. H., Davies, T. G., Dinan, L. N., Lockley, W. J. S., and Goodwin, T. W., in: Progress in Ecdysone Research, p. 125. Ed. J. A. Hoffmann. Elsevier/North Holland, Amsterdam 1980.Google Scholar
  20. 21.
    ForOncopeltus: Svoboda, J. A., Dutky, S. R., Robbins, W. E., and Kaplanis, J. N., Lipids12 (1977) 318.Google Scholar
  21. 22.
    ForNezara: Aldrich, J. R., Svoboda, J. A., and Thompson, M. J., unpublished results.Google Scholar
  22. 23.
    Svoboda, J. A., Lusby, W. R., and Aldrich, J. R., Archs Insect Biochem. Physiol., in press.Google Scholar
  23. 24.
    Stys, P., and Kerzhner, J., Acta ent. bohemoslav.72 (1975) 65.Google Scholar
  24. 25.
    Mention of a commercial or proprietary product does not constitute a recommendation for use by the U.S. Department of Agriculture.Google Scholar

Copyright information

© Birkhäuser Verlag 1984

Authors and Affiliations

  • T. J. Kelly
    • 1
  • J. R. Aldrich
    • 1
  • C. W. Woods
    • 1
  • A. B. Borkovec
    • 1
  1. 1.Insect Reproduction and Insect Physiology Laboratories, Agricultural Research ServiceU.S. Department of AgricultureBeltsvilleUSA

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