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Local action of vitamin A on amphibian limb regeneration

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Summary

Axolotl forearms isolated from upper arm tissue either surgically or by local irradiation regenerate excessive structures after vitamin A treatment. This demonstration excludes the possibility of regeneration being altered by enhanced cellular migration and thus indicates that vitamin A respecifies cells close to the site of amputation.

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Wallace, H., Maden, M. Local action of vitamin A on amphibian limb regeneration. Experientia 40, 985–986 (1984). https://doi.org/10.1007/BF01946471

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  • DOI: https://doi.org/10.1007/BF01946471

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