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Characterization of the third component of pig complement and its utilization in a C3b receptor study

Experientia volume 40, pages 975–977 (1984)Cite this article

Summary

The third component of the pig complement system (C3) was isolated in hemolytically active form and characterized. The C3 component is a β-globulin with the molecular weight of 191,000 and is composed of 2 non-identical polypeptide chains of Mt 112,000 and 74,000. The isolated C3 can be used for the detection of the C3b receptor on the membranes of heterologous peritoneal macrophages.

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Affiliations

  1. Institute of Microbiology, Department of Immunology, Czechoslovak Academy of Sciences, Vídeňská 1083, 14220, Prague 4, (Czechoslovakia)

    J. Zídková, V. Větvička, P. Rossmann, V. Dlabač & J. Stránsky

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  1. J. Zídková
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  2. V. Větvička
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  3. P. Rossmann
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  4. V. Dlabač
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  5. J. Stránsky
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Zídková, J., Větvička, V., Rossmann, P. et al. Characterization of the third component of pig complement and its utilization in a C3b receptor study. Experientia 40, 975–977 (1984). https://doi.org/10.1007/BF01946467

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  • DOI: https://doi.org/10.1007/BF01946467

Key words

  • Complement
  • pig
  • complement
  • system
  • C3b receptor
  • β-globulin
  • macrophages