Summary
The rates of secretion of cholesterol in bile measured by an isotope ratio method were found similar in cholesterol-fed high- and low-responding rhesus monkeys. The results indicate that the failure on the part of the high-responders to increase proportionately the fecal excretion of neutral steroids to compensate for the higher absorption of cholesterol than the low-responders, as suggested earlier, is not due to a difference in the rate of biliary cholesterol secretion but must lie in some other aspect of cholesterol metabolism.
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Acknowledgments. The study was financed by the research grant HL-08974 from the National Heart, Lung, Blood Institute, National Institutes of Health, Bethesda, Maryland.
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Bhattacharyya, A.K., Eggen, D.A. The rate of biliary cholesterol secretion in high-and low-responding rhesus monkeys. Experientia 42, 1227–1228 (1986). https://doi.org/10.1007/BF01946397
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DOI: https://doi.org/10.1007/BF01946397