Experientia

, Volume 29, Issue 7, pp 874–876 | Cite as

Central glucoprivation: Some physiological effects induced by the intraventricular administration of 2-deoxy-d-glucose

  • E. E. Müller
  • A. Panerai
  • Daniela Cocchi
  • L. A. Frohman
  • P. Mantegazza
Specialia

Keywords

Physiological Effect Intraventricular Administration 

Riassunto

Il 2-desossi-d-glucosio somministrato nel ventricolo laterale del cervello del ratto provoca iperglicemia, inibizione della secrezione di insulina, iperfagia ed ipotermia a dosi che sono inefficaci per via sistemica.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    A. N. Wick, D. R. Drury, H. Nakada andJ. B. Wolfe, J. biol. Chem.224, 963 (1957).Google Scholar
  2. 2.
    G. P. Smith andA. N. Epstein, Am. J. Physiol.217, 1083 (1969).Google Scholar
  3. 3.
    S. J. Goldsmith, R. S. Yalow andS. A. Berson, Diabetes19, 453 (1970).Google Scholar
  4. 4.
    G. P. Smith andA. W. Root, Endocrinology85, 963 (1969).Google Scholar
  5. 5.
    B. Hökfelt andS. Bydgeman, Proc. Soc. exp. Biol. Med.106, 537 (1961).Google Scholar
  6. 6.
    J. Laszlo, W. R. Harlan, R. F. Klein, N. Kirshner, E. H. Estes Jr. andM. D. Bogdanof, J. clin. Invest.40, 171 (1961).Google Scholar
  7. 7.
    F. B. Altaffer, F. de Balbian Verster, S. Hall, G. J. Long andP. D'Encarnacao, Physiol. Behav.5, 119 (1970).Google Scholar
  8. 8.
    C. Rerup andI. Lundquist, Acta endocr. copenh.52, 357 (1966).Google Scholar
  9. 9.
    L. A. Frohman andL. L. Bernardis, Endocrinology82, 1125 (1968).Google Scholar
  10. 10.
    J. Mayer, Physiol. Rev.33, 472 (1953).Google Scholar
  11. 11.
    R. W. Reynolds andJ. Kimm, J. comp. Physiol.60, 438 (1965).Google Scholar
  12. 12.
    S. Balagura, M. Kanner, Physiol. Behav.7, 252 (1971).Google Scholar
  13. 13.
    R. R. Miselis andA. N. Epstein, Physiologist13, 262 (1970).Google Scholar
  14. 14.
    InNeural Regulation of Food and Water Intake Ed.P. J. Morgane; Ann. N.Y. Acad. Sci.157, 531–1216 (1969).Google Scholar
  15. 15.
    B. G. Hoebei, A. Rev. Physiol.33, 533 (1971).Google Scholar
  16. 16.
    S. P. Grossman, Fedn. Proc.27, 1349 (1968).Google Scholar
  17. 17.
    N. Kokka andR. George, Neuroendocrinology6, 1 (1970).Google Scholar
  18. 18.
    T. Desiraju, M. G. Banerjee andB. K. Anand, Physiol. Behav.3, 757 (1968).Google Scholar
  19. 19.
    D. G. Colin-Jones andR. L. Himsworth, J. Physiol., Lond.206, 397 (1970).Google Scholar
  20. 20.
    R. L. Himsworth, P. W. Carmel, A. G. Frantz, Endocrinology91, 217 (1972).Google Scholar
  21. 21.
    J. R. Brobeck, Yale J. Biol. Med.20, 545 (1947–48).Google Scholar

Copyright information

© Birkhäuser Verlag 1973

Authors and Affiliations

  • E. E. Müller
    • 1
  • A. Panerai
    • 1
  • Daniela Cocchi
    • 1
  • L. A. Frohman
    • 1
  • P. Mantegazza
    • 1
  1. 1.2nd Chair Department of PharmacologyUniversity of MilanMilanoItaly

Personalised recommendations