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Pentobarbital-induced increase of rat liver phosphoprotein phosphatase

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Résumé

Le pentobarbital provoque un accroissement important de l'activité de la phosphoprotein-phosphatase extramicrosomiale du foie du rat. L'accroissement de l'activité de l'enzyme se produit dejà 20 min après l'administration du médicament (+40%) et dure autant que le traitement (+50–70%). Le niveau de l'induction dépend de la dose du pentobarbital. L'induction est bloquée par l'administration simultanée du cycloheximide ou du SKF 525-A.

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Authors and Affiliations

  1. Faculty of Medecine, Institute of Biochemistry and Institute of Histology, Beograd, (Yugoslavia)

    J. Mimić-Oka, I. Japundžić & M. Japundžić

Authors
  1. J. Mimić-Oka
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  2. I. Japundžić
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  3. M. Japundžić
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Mimić-Oka, J., Japundžić, I. & Japundžić, M. Pentobarbital-induced increase of rat liver phosphoprotein phosphatase. Experientia 28, 1160–1161 (1972). https://doi.org/10.1007/BF01946143

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