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The amino acid composition of rat bile

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Summary

The pattern of amino acids in the bile of rats differs from the pattern in the serum of these animals, since bile contains significantly greater amounts of acidic and sulphur-containing amino acids and glycine than serum, while the serum contained more basic amino acids than bile, indicating that secretion of amino acids into bile may involve specific transport processes.

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Author notes

  1. U. R. Fölsch

    Present address: DW of Gastroenterology and Metabolism, Department of Medicine, University of Göttingen, D-34, Göttingen, Germany

  2. K. G. Wormsley

    Present address: Ninewells Hospital, DD2 1UB, Dundee, Scotland

Authors and Affiliations

  1. Department of Therapeutics, University of Dundee, DD2 1UB, Dundee, Scotland

    U. R. Fölsch & K. G. Wormsley

Authors
  1. U. R. Fölsch
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  2. K. G. Wormsley
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Additional information

Acknowledgments. We thank Mr M. Earlam of Pharmaceuticals Division, Imperial Chemical Industries Limited for the aminoacid analyses, and Dr J. S. Morley for helpful discussion. URF gratefully acknowledges a grant (FO 73/2) from the Deutsche Forschungsgemeinschaft, Bonn-Bad Godesberg, Fed. Rep. of Germany. KGW is recipient of a grant from the Scottish Hospital Research Endowments Trust.

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Fölsch, U.R., Wormsley, K.G. The amino acid composition of rat bile. Experientia 33, 1055–1056 (1977). https://doi.org/10.1007/BF01945966

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  • DOI: https://doi.org/10.1007/BF01945966

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