Summary
Female mice which displayed a vaginal plug after mating were given a diet containing 0, 0.125, 0.250, 0.500% of lead as lead acetate and were dissected 16 to 18 days later. Lead treatment was found to reduce significantly the incidence of pregnancies and to increase the postimplantation loss in the pregnant females.
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References
C. Paul, Arch. gen. Med.15, 513 (1860).
A. Hall, Br. med. J.1, 584 (1905).
H. A. Schroeder andM. M. Mitchener, Arch. envir. Health23, 102 (1971).
H. A. Schroeder, M. M. Mitchener andA. P. Nason, J. Nutrition100, 59 (1970).
A. Léonard, G. Linden andG. B. Gerber, Proc. Int. Symp. Envir. Health Aspects of Lead, Amsterdam, EUR 5004 d-e-f (1973), p. 303.
A. Azar, H. J. Trochimowicz andM. E. Maxfield, Proc. Int. Symp. Envir. Health Aspects of Lead, Amsterdam, EUR 5004 d-e-f (1973), p. 199.
D. C. Jessup The Chromic Toxicity of Lead, American Petroleum Institute Medical Research (1971), Report No. EA 7102.
V. H. Ferm andD. W. Ferm, Life Sci.10, 35 (1971).
P. E. Fournier andE. Rosenberg, Proc. Int. Symp. Envir. Health Aspects of Lead, Amsterdam, EUR 5004 d-e-f (1973), p. 287.
J. L. Shupe, W. Binns, L. F. James andR. F. Keeler, J. Am. vet. med. Ass.151, 198 (1967).
L. F. James, V. A. Lazar andW. Binns, Am. J. vet. Res.27, 132 (1966).
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Jacquet, P., Léonard, A. & Gerber, G.B. Embryonic death in mouse due to lead exposure. Experientia 31, 1312–1313 (1975). https://doi.org/10.1007/BF01945798
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DOI: https://doi.org/10.1007/BF01945798