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Trigilletimine: A newBisbenzylisoquinoline alkaloid fromTriclisia species

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  • Chimica, Biochimica
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Summary

The structure of trigilletimine (1), a newbisbenzylisoquinoline dibenzodioxin alkaloid fromTriclisia gilletii (De Wild.) Staner andT. patens Oilv., was determined by spectral means and conversion to the N-methyltetrahydro derivative.

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References

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Author notes

  1. D. Dwuma-Badu & J. S. K. Ayim

    Present address: Faculty of Pharmacy, University of Science and Technology, Kumasi, Ghana

  2. A. N. Tackie

    Present address: Council for Scientific and Industrial Research, Accra, Ghana

  3. M. A. El Sohly, J. E. Knapp, D. J. Slatkin & P. L. Schiff Jr.

    Present address: Department of Pharmacognosy, School of Pharmacy, University of Pittsburgh, 512 Salk Hall, 15261, Pittsburgh, Pennsylvania, USA

Authors and Affiliations

  1. Faculty of Pharmacy, University of Science and Technology, Kumasi, Ghana

    A. N. Tackie, M. A. El Sohly, J. E. Knapp, D. J. Slatkin & P. L. Schiff Jr.

  2. Council for Scientific and Industrial Research, Accra, Ghana

    D. Dwuma-Badu, J. S. K. Ayim, M. A. El Sohly, J. E. Knapp, D. J. Slatkin & P. L. Schiff Jr.

  3. Department of Pharmacognosy, School of Pharmacy, University of Pittsburgh, 512 Salk Hall, 15261, Pittsburgh, Pennsylvania, USA

    D. Dwuma-Badu, J. S. K. Ayim & A. N. Tackie

Authors
  1. D. Dwuma-Badu
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  2. J. S. K. Ayim
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  3. A. N. Tackie
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  4. M. A. El Sohly
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  5. J. E. Knapp
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  6. D. J. Slatkin
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  7. P. L. Schiff Jr.
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Additional information

Part XII in the series ‘Constituents of West African Medicinal Plants’. For Part XI seeD. Dwuma-Badu, J. S. K. Ayim, A. N. Tackie, J. E. Knapp, D. J. Slatkin andP. L. Schiff, jr., Phytochemistry, in press (1975).

We thank ProfessorI. R. C. Bick, University of Tasmania, Hobart, Tasmania, Australia 7001 for gifts of samples and spectra; Mr.John Naworal, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, Pennsylvania 15261 and Mr.John Occolowitz, Eli Lilly and Co., Indianapolis, Indiana for determining the mass spectra. This investigation was supported in part by a grant from the African-American Scholars Council and by Research Grant No. 5S01RR05455-10 from the National Institutes of Health, Education and Welfare. The mass spectrometer facility was supported by Research Grant No. RR-00273 to the University of Pittsburgh from the National Institutes of Health.

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Dwuma-Badu, D., Ayim, J.S.K., Tackie, A.N. et al. Trigilletimine: A newBisbenzylisoquinoline alkaloid fromTriclisia species. Experientia 31, 1251–1252 (1975). https://doi.org/10.1007/BF01945760

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  • DOI: https://doi.org/10.1007/BF01945760

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