Résumé
L'administration d'acide fusarique, un inhibiteur de la dopamine-β-oxidase, a supprimé électivement le sommeil REM, sans influence significative sur le sommeil lent. Le rôle de noradrénaline dans le mécanisme central du sommeil REM est discuté.
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Fusaric acid was available through the courtesy of Dr.T. Nagatsu, Department of Biochemistry, School of Dentistry, Aichi-Gakuin University. Thanks are due to Dr.L. M. Vernon for bis reading of the manuscript. This work was supported in part by a grant from Japan Society for Promotion of Science under contract No. 5R023.
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Satoh, T., Tanaka, R. Selective suppression of rapid eye movement sleep (REM) by fusaric acid, an inhibitor of dopamine-β-oxidase. Experientia 29, 177–178 (1973). https://doi.org/10.1007/BF01945459
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DOI: https://doi.org/10.1007/BF01945459