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Evidence for a different site of action of phenoxybenzamine and desmethylimipramine on the catecholamine uptake system

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Resumen

El tratamiento con fenoxibenzamina o desmetilimipramina da lugar a una potenciación irreversible de las respuestas a noradrenalina, en la aurícula aislada de cobayo. La presencia de tiramina durante el tratamiento previene dicha potenciación cuando se utiliza fenoxibenzamina, mientras que no la modifica en el caso de la desmetilimipramina

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Authors and Affiliations

  1. Departmento de Farmacologia, Facultad de Medicina, Ciudad Universitaria, Madrid-3, Spain

    A. Garcia Garcia, A. Velasco Martin, R. Martinez Sierra & P. Sánchez Garcia

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  1. A. Garcia Garcia
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  2. A. Velasco Martin
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  3. R. Martinez Sierra
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  4. P. Sánchez Garcia
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Garcia, A.G., Martin, A.V., Sierra, R.M. et al. Evidence for a different site of action of phenoxybenzamine and desmethylimipramine on the catecholamine uptake system. Experientia 28, 671–673 (1972). https://doi.org/10.1007/BF01944970

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