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A method for distinguishing Tetrodotoxin from Saxitoxin, by comparing their relative stabilities when heated in acid solution

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La tetrodotoxina pierde toxicidad rapidamente cuando se calienta en solución acida por debajo de pH 2, mientras que la saxitoxina es estable. Se puede distinguir facilmente entre estos venenos calentándolos a 100°C en solution pH 1.0 durante 20–30 min.

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This work was carried out whileC. J. Waterfield was on industrial training leave from Bath University of Technology. We wish to thank MissJ. Tulloch for her assistance.

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Waterfield, C.J., Evans, M.H. A method for distinguishing Tetrodotoxin from Saxitoxin, by comparing their relative stabilities when heated in acid solution. Experientia 28, 670–671 (1972). https://doi.org/10.1007/BF01944969

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