Zusammenfassung
Die Messung des Denaturationsdunktes als Parameter für die thermale Reaktion des Kollagens in geometrisch komplexen Geweben oder von Kollagenen verschiedener Reifegrade wird beschrieben und Beispiele im Bereich von Altersunterschieden und Wundheilung werden gegeben.
Literatur
A. Viidik, inAging of Connective and Skeletal Tissues (Eds.A. Engel andT. Larsson; Nordiska Bokhandeln, Stockholm 1969), p. 125.
P. J. Flory andR. R. Garrett, J. Am. chem. Soc.80, 4836 (1958).
F. Verzár, Experientia11, 230 (1955).
F. Verzár, Helv. physiol. pharmac. Acta13, 64 (1955).
P. J. Flory, J. Am. chem. Soc.78, 5222 (1956).
P. J. Brown andR. Consden, Nature, Lond.181, 349 (1958).
K. T. Joseph andS. M. Bose, inCollagen (Ed.N. Ramanathan; Interscience Publisher, New York 1962), p. 371.
D. M. Rasmussen, G. W. Khalil andR. K. Winkelmann, J. invest. Derm.43, 333 (1964).
S. Ja. Frenkelj, L. V. Cuchareva, I. M. Ginsjurg, K. A. Gaspar-Jan andV. I. Vorobjev, Biofizika10, 735 (1965).
L. Klein, B. D. Garg andC. J. Nowacek, Biochem. biophys. Res. Commun.34, 8 (1969).
P. Holm-Pedersen andA. Viidik, unpublished data (1971).
D. M. Douglas, inWound Healing (Ed.C. Illingworth; Churchill, London 1966), p. 233.
Author information
Authors and Affiliations
Additional information
This work was supported by Swedish Medical Research Council (Project No. B70-12X-2883-01) and by Carin Trygger Memorial Fund through the Swedish Society of Medical Sciences and performed at the Department of Anatomy, University of Gothenburg, Sweden.
The technical assistance of MissUlla-Britt Lindgren in the development of this method is gratefully acknowledged.
Rights and permissions
About this article
Cite this article
Viidik, A. Aging of collagen in complex tissues. A micromethodological study of the thermal reaction. Experientia 28, 641–642 (1972). https://doi.org/10.1007/BF01944950
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01944950