, Volume 34, Issue 2, pp 262–263 | Cite as

Changes in placental permeability to corticosterone and estradiol-17β toward the end of gestation in the rat

  • K. Arishima
  • S. Nakama
  • Y. Morikawa
  • Y. Hashimoto
  • Y. Eguchi


Radioactivity in the fetal plasma 1 h after maternal injection of14C-4-corticosterone or14C-4-estradiol-17β on day 21 of gestation was markedly higher than that 1 h after injection on day 22. Radioactivity in the maternal plasma was not different on these 2 days. The results suggest that the placental permeability to steroids from the mother to the fetus declines toward the end of gestation in the rat.


Permeability Steroid Corticosterone Maternal Plasma Fetal Plasma 
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Copyright information

© Birkhäuser Verlag 1978

Authors and Affiliations

  • K. Arishima
    • 1
  • S. Nakama
    • 1
  • Y. Morikawa
    • 1
  • Y. Hashimoto
    • 1
  • Y. Eguchi
    • 1
  1. 1.Departments of Veterinary Anatomy and Surgery, College of AgricultureUniversity of Osaka PrefectureSakai City OsakaJapan

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