, Volume 34, Issue 2, pp 216–217 | Cite as

An escape phenomenon from water and sodium retention induced by propranolol in rats

  • J. M. López-Novoa
  • S. Casado
  • L. Hernando


Rats given a daily dose of propranolol 45 mg/kg b.wt retain water and sodium for 4 days, escaping during the 5th and 6th days in which their excretions are larger than basal values. Afterwards, in the period studied, they make a new retention and clearing is less accentuated. No relationship could be found between these retentions and plasma renin activity or renal renin content.


Sodium Propranolol Renin Plasma Renin Activity Plasma Renin 
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Copyright information

© Birkhäuser Verlag 1978

Authors and Affiliations

  • J. M. López-Novoa
    • 1
  • S. Casado
    • 1
  • L. Hernando
    • 1
  1. 1.Servicio de NefrologíaFundación Jiménez DíazMadrid 3Spain

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