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In vivo and in vitro studies on irreversible binding of halothane metabolites to proteins

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Zusammenfassung

Die Bindung von14C-Halothanmetaboliten an mikrosomales Protein wurde in vitro in mikrosomalen Inkubationen und in vivo and der Maus untersucht. Tryptische Spaltung des Proteins zeigt, dass die Radioaktivität kovalent gebunden ist.

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Authors and Affiliations

  1. Institut für Toxikologie der Universität Tübingen, Wilhelmstrasse 56, D-74, Tübingen, Germany

    V. Hempel & H. Remmer

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  1. V. Hempel
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  2. H. Remmer
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Hempel, V., Remmer, H. In vivo and in vitro studies on irreversible binding of halothane metabolites to proteins. Experientia 31, 680–681 (1975). https://doi.org/10.1007/BF01944625

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