Experientia

, Volume 33, Issue 6, pp 753–754 | Cite as

Distribution of14C after topical application of14C-labeled 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) in mice

  • H. S. Zackheim
  • R. J. Feldmann
  • C. Lindsay
  • H. I. Maibach
Article

Summary

Following topical application of14C-labeled 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU, carmustine) to the skin of mice radioactivity was found in all viscera and tissues examined. Exclusive of the gut, highest values were recorded for the liver, kidney and lung.

Keywords

Topical Application BCNU Carmustine Nitrosourea 

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Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • H. S. Zackheim
    • 1
  • R. J. Feldmann
    • 1
  • C. Lindsay
    • 1
  • H. I. Maibach
    • 1
  1. 1.Department of DermatologyUniversity of California Medical CenterSan FranciscoUSA

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