, Volume 33, Issue 6, pp 741–742 | Cite as

The effect of fluorocitrate on urinary calcium and citrate excretion

  • G. O. Perez
  • G. Frindt


The renal handling of calcium and citrate was studied in dogs after the administration of fluorocitrate. The drug produced a significant increase in urinary calcium and citrate excretion. Net renal secretion of citrate occurred during the infusion of fluorocitrate since citrate clearances exceeded the glomerular filtration rate.


Calcium Filtration Citrate Glomerular Filtration Rate Glomerular Filtration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 2.
    T. S. Chang and S. Freeman, Am. J. Physiol.160, 330 (1950).Google Scholar
  2. 3.
    E. Shorr, T. P. Almy, M. H. Sloan, H. Taussky and V. Toscani, Science96, 587 (1942).Google Scholar
  3. 4.
    E. Shorr, J. Urol.53, 507 (1945).Google Scholar
  4. 5.
    O. SOsterberg, Skand. Arch. Physiol.62, 81 (1931).Google Scholar
  5. 6.
    J. Karam, M. T. Harrison, M. Hartog and R. Fraser, Clin. Sci.21, 265 (1961).Google Scholar
  6. 7.
    R. A. Peters, Adv. Enzymol.18, 113 (1957).Google Scholar
  7. 8.
    H. Moellering and W. Gruber, Analyth. Biochem.17, 369 (1966).Google Scholar
  8. 9.
    C. M. Elwood and E. M. Sigman, Circulation36, 441 (1967).Google Scholar
  9. 10.
    E. E. Gordon, J. clin. Invest40, 1719 (1961).Google Scholar
  10. 11.
    Z. S. Agus, L. B. Gardner, L. H. Beck and M. Goldberg, Am. J. Physiol.224, 1143 (1973).Google Scholar
  11. 12.
    S. Czekalski, N. Loreau, F. Paillard, R. Ardaillou, J. P. Fillastre and E. Mallet, Eur. J. clin. Invest.4, 85 (1974).Google Scholar
  12. 13.
    S. B. Baruch, R. L. Burich, C. K. Eun and V. F. King, Med. Clins N. Am.59, 569 (1975).Google Scholar
  13. 14.
    J. A. Gagnon, R. W. Schrier, T. P. Weis, W. Kokotis and L. Mailloux, J. Appl. Physiol.30, 774 (1971).Google Scholar
  14. 15.
    Y. K. Kook and W. D. Lotspeich, Am. J. Physiol.215, 282 (1968).Google Scholar

Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • G. O. Perez
    • 3
    • 1
    • 2
  • G. Frindt
    • 3
    • 1
    • 2
  1. 1.Departments of MedicineUniversity of Miami School of MedicineMiamiUSA
  2. 2.Catholic University School of MedicineSantiago(Chile)
  3. 3.Dialysis Unit (111C)Veterans Administration HospitalMiamiUSA

Personalised recommendations