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Kinetic behaviour of microsomal styrene monooxygenase and styrene epoxide hydratase in different animal species

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Summary

The apparent Km and Vmax values of styrene epoxide forming monooxygenase and styrene epoxide hydratase have been evaluated in the liver microsomes of male rats, mice, guinea-pigs and rabbits. Epoxide hydratase gave much higher and more uniform Km values than the monooxygenase in the species considered.

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References

  1. D. M. Jerina and J. W. Daly, Science185, 573 (1974).

    Article  CAS  PubMed  Google Scholar 

  2. F. Oesch, Xenobiotica3, 305 (1973).

    Article  CAS  PubMed  Google Scholar 

  3. R. Kato and M. Takayanaghi, Jap. J. Pharmac.16, 380 (1966).

    Article  CAS  Google Scholar 

  4. O. H. Lowry, N. J. Rosebrough, A. L. Farr and R. J. Randall, J. biol. Chem.193, 265 (1951).

    Article  CAS  PubMed  Google Scholar 

  5. G. Belvedere, J. Pachecka, L. Cantoni, E. Mussini and M. Salmona, J. Chromat.118, 387 (1976).

    Article  CAS  Google Scholar 

  6. D. A. Haugen, M. J. Coon and D. W. Nebert, J. biol. Chem.,251, 1817 (1976).

    Article  CAS  PubMed  Google Scholar 

  7. M. T. Huang, S. B. West and A. Y. H. Lu, J. biol. Chem.,251, 4659 (1976).

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Laboratory for Enzyme Research, Istituto di Ricerche Farmacologiche ‘Mario Negri’, Via Eritrea 62, I-20157, Milano, Italy

    G. Belvedere, L. Cantoni, T. Facchinetti & M. Salmona

Authors
  1. G. Belvedere
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  2. L. Cantoni
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  3. T. Facchinetti
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  4. M. Salmona
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Additional information

Acknowledgments. This work has been partially supported by the Fondazione Valenti (Milano). To whom enquiries should be addressed.

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Belvedere, G., Cantoni, L., Facchinetti, T. et al. Kinetic behaviour of microsomal styrene monooxygenase and styrene epoxide hydratase in different animal species. Experientia 33, 708–709 (1977). https://doi.org/10.1007/BF01944141

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  • DOI: https://doi.org/10.1007/BF01944141

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