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Effect of a brain-specific protein (S-100 protein) on the nucleolar RNA polymerase activity in isolated brain nuclei

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Una proteina specifica del sistema nervoso, chiamata S-100, stimola la RNA polimerase nucleolare in nuclei isolati da encefalo immaturo di pollo (11 giorni di incubazione). La proteina non ha alcum effetto sulla RNA polimerase nucleoplasmica del medesimo sistema sperimentale. La stimolazione della S-100 sulla RNA polimerase nucleolare è α-amanitina resistente ed è parzialmente antagonizzata dalla actinomicina. Ulteriori ricerche potranno chiarire il ruolo della proteina S-100 sulla espressione genetica del sistema nervoso.

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References

  1. B. W. Moore, Biochem. biophys. Res. Commun.19, 739 (1965).

    Article  CAS  Google Scholar 

  2. L. Levine andB. W. Moore, Neurosci. Res. Prog. Bull.3, 18 (1965).

    Google Scholar 

  3. B. W. Moore, V. J. Perez andM. J. Gebring, J. Neurochem.15, 265 (1968).

    Article  CAS  Google Scholar 

  4. D. Kessler, L. Levine andG. Fasman, Biochemistry7, 758 (1968).

    Article  CAS  Google Scholar 

  5. T. J. Cicero, W. M. Cowan, B. W. Moore andV. Suntzeff, Brain Res.18, 25 (1970).

    Article  CAS  Google Scholar 

  6. N. Miani, G. de Renzis, F. Michetti, S. Correr, C. Olivieri Sangiacomo andA. Caniglia, J. Neurochem.19, 1387 (1972)

    Article  CAS  Google Scholar 

  7. E. de Robertis, Science156, 907 (1967).

    Article  Google Scholar 

  8. J. E. Zuckerman, H. R. Herschman andL. Levine, J. Neurochem.17, 247 (1970).

    Article  CAS  Google Scholar 

  9. P. Calissano andA. D. Bangham, Biochem. biophys. Res. Commun.43, 504 (1971).

    Article  CAS  Google Scholar 

  10. H. Hydén andP. W. Lange, Expl Cell Res.62, 125 (1970).

    Article  Google Scholar 

  11. F. Michetti, N. Miani, G. de Renzis, A. Caniglia andS. Correr,Proteins of the Nervous System (N.A.T.O. Advanced Study Institute, Cortona 1972).

    Google Scholar 

  12. N. Montanaro, F. Novello andF. Stirpe, Biochem. J.125, 1087 (1971).

    Article  CAS  Google Scholar 

  13. K. Burton, Biochem. J.62, 315 (1956).

    Article  CAS  Google Scholar 

  14. G. R. Dutton andH. R. Mahler, J. Neurochem.15, 765 (1968).

    Article  CAS  Google Scholar 

  15. H. Løvtrup-Rein andB. S. McEwen, J. Cell Biol.30, 405 (1966).

    Article  Google Scholar 

  16. B. W. Moore,Handbook of Neurochemistry (Ed.A. Lajtha, Plenum Press, New York 1969), Vol. 1, p. 93.

    Google Scholar 

  17. S. C. Bondy andS. Roberts, Biochem. J.115, 341 (1969).

    Article  CAS  Google Scholar 

  18. T. J. Cicero, M. W. Cowan andB. W. Moore, Brain Res.24, 1 (1970).

    Article  CAS  Google Scholar 

  19. B. Wenger andH. Friedman, Nature, Lond.228, 1214 (1970).

    Article  CAS  Google Scholar 

  20. T. J. Cicero andR. R. Provine, Brain Res.44, 294 (1972).

    Article  CAS  Google Scholar 

  21. This work was partially supported by C.N.R. Contracts No. 71.00856.04 and No. 72.00817.04.

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Authors and Affiliations

  1. Istituto di Anatomia Umana Normale, Università cattolica del Sacro Cuore, Via della Pineta Sacchetti 644, I-00168, Roma, Italia

    N. Miani, F. Michetti, G. de Renzis & A. Caniglia

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  1. N. Miani
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  2. F. Michetti
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  3. G. de Renzis
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  4. A. Caniglia
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Miani, N., Michetti, F., de Renzis, G. et al. Effect of a brain-specific protein (S-100 protein) on the nucleolar RNA polymerase activity in isolated brain nuclei. Experientia 29, 1499–1501 (1973). https://doi.org/10.1007/BF01943879

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