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Studies on the quaternary structure of the first enzyme for histidine biosynthesis

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Se han realizado estudios de asociación-disociación por filtración en gel con el primer enzima de la biosíntesis de histidina enEscherichia coli, en presencia de sustratos y ligandos. Se observa una interconversión reversible entre las formas dímero, tetrámero y exámero, y una agregación irreversible de orden superior.

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  20. Acknowledgements. We thankJ. F. García de la Banda for his support, encouragement and helpful discussions,A. Albert for permission to use his Department's equipment and him andA. Cortés for critical reading of the manuscript, andS. M. Parsons andD. E. Koshland for communicating their results prior to publication.J. A. Amigo andJ. Vega-Leal contributed skilled technical assistance. This work was supported by the Plan de Formación de Personal Investigador.

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Authors and Affiliations

  1. Departamento de Catálisis, Consejo Superior de Investigaciones Cientificas, Serrano 119, Madrid 6, Spain

    A. R. Tébar, V. M. Fernández, R. MartinDelRío & A. O. Ballesteros

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  1. A. R. Tébar
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  2. V. M. Fernández
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  3. R. MartinDelRío
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  4. A. O. Ballesteros
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Tébar, A.R., Fernández, V.M., MartinDelRío, R. et al. Studies on the quaternary structure of the first enzyme for histidine biosynthesis. Experientia 29, 1477–1479 (1973). https://doi.org/10.1007/BF01943865

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  • DOI: https://doi.org/10.1007/BF01943865

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