Skip to main content
SpringerLink
Log in

Creatinine: A precursor of methylguanidine

  • Specialia
  • Published:
Experientia Aims and scope Submit manuscript

Zusammenfassung

Intraperitoneale Zufuhr von14CH3-Kreatinin in Ratten erhöht deren 24-h-Ausscheidung von radiomarkiertem Methyl-Guanidin im Urin, während Tiere, die andere radiomarkierte potentielle Vorläufer erhalten hatten, keine erhöhte Ausscheidung zeigten. Diese in-vivo-Konversion von Kreatinin zu Methyl-Guanidin konnte nicht der Aktion gastrointestinaler Bakterien zugeschrieben werden, da die Ausscheidung von Methyl-Guanidin sowohl in antibiotikabehandelten als auch in sterilen Ratten übereinstimmte.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. I. M. Stein, G. Perez, R. Johnson andN. B. Cummings, J. Lab. clin. Med.77, 1020 (1971).

    CAS  Google Scholar 

  2. S. Giovanetti, M. Biagini, P. L. Balestri, R. Navalesi, P. Giognoni, A. DeMatteis, P. Ferro-Miloni andC. Perfetti, Clin. Sci.36, 445 (1969).

    Google Scholar 

  3. K. Bloch andR. Schoenheimer, J. biol. Chem.131, 111 (1939).

    Article  CAS  Google Scholar 

  4. O. Voges andB. Z. Proskauer, Hyg. Infektionskrankh.28, 20 (1898).

    Article  Google Scholar 

  5. J. J. Pfiffner andC. V. Myers, J. biol. Chem.87, 345 (1930).

    Article  CAS  Google Scholar 

  6. R. Dubos andB. F. Miller, J. biol. Chem.121, 429 (1937).

    Article  CAS  Google Scholar 

  7. H. G. van Eyk, R. J. Vermaat, H. J. Leijnse-Ybema andB. Leynse, Enzymologia34, 198 (1968).

    CAS  Google Scholar 

  8. J. D. Jones andP. C. Burnett, Clin. Chem.18, 280 (1972).

    Article  CAS  Google Scholar 

  9. R. Goldman, Proc. Soc. exp. Biol. Med.85, 446 (1954).

    Article  CAS  Google Scholar 

  10. S. Giovanetti, P. L. Balestri andG. Barsotti, Archs intern. Med.131, 709 (1973).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Medicine, University of Miami School of Medicine, Veterans Administration Hospital, 1201 NW 16th Street, 33125, Miami, Florida, USA

    G. Perez & R. Faluotico

Authors
  1. G. Perez
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Faluotico
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Perez, G., Faluotico, R. Creatinine: A precursor of methylguanidine. Experientia 29, 1473–1474 (1973). https://doi.org/10.1007/BF01943863

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01943863

Keywords

Search

Navigation